Mimusops elengi Linn (Sapotaceae) commonly known as Bakul, is a small to large evergreen tree. It is cultivated in gardens as an ornamental tree. Bark is used as a tonic, febrifuge, against odontopathy, inflammation. The part of plants was used in Thai traditional community as rejuvenating and neuro tonic, also Mimusops elengi is being screened for acetyl cholinesterase inhibitory activity. Despite the widespread uses of the plant, no scientific work is reported in literature regarding the effect of Mimusops elengi bark on memory and anxiety like states hence , the present study evaluates effect of methanolic, aqueous and n-butanol extract of bark of Mimusops elengi in swiss albino mice. Different doses of Test extract was evaluated in animals. Methanol extract at 50,100 and 200 mg/kg, aqueous extract at 100 and 200 while n-butanol extract at 200 mg/kg in mice were active but methanolic extract at 200 mg/kg was found to have more significant activity as compared to aqueous and n-butanol extract.
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